Revolutionary imaging system opens a new frontier for researchers, utilizing the world's most sensitive and highest resolution SPECT system combined with a compact high-performance MRI system for exceptional soft tissue contrast

Dublin, Ireland - Today, Mediso Medical Imaging Systems unveiled its new system, nanoScan® SPECT/MRI, the world's first commercial in-line integrated preclinical SPECT/MRI imaging system at the World Molecular Imaging Congress (WMIC), 2012, in Dublin, Ireland.

"The nanoScan® SPECT/MRI system integrates our proprietary and patented* M3-pinhole™ technology and Tera-Tomo™ 3D SPECT reconstruction algorithm with the integrated compact cryogen-free high-performance MRI system from Aspect Imaging" says István Bagaméry, founder and CEO of Mediso. "This unique innovative integrated system delivers twice the sensitivity and volumetric resolution than the previously manufactured system and enables ultrafast quantitative dynamic imaging that is unfounded in the preclinical imaging field."
At the heart of the SPECT component is the proprietary M3-pinhole™ technology. Unlike analogue detectors used in previous generation, new fully digital detectors break down the former limitations on sensitivity, resolution and artefact-free imaging. The active surface and thickness of the SPECT crystals have been increased by 50% on all four heads and the larger useful field of view is perfectly covered by rectangular projections. Multiplexing of pinhole projections is avoided by applying 100 pinholes enabling imaging that is free from artefacts that traditionally originated from overlapping.

In addition to the conventional helical scanning schemes, the increased number of projections per detector head allows true stationary acquisitions without any rotation or table movements.

Raw data is acquired and stored in full list mode format supporting flexible processing and ultrafast dynamic imaging. Quantitative results are delivered by the proprietary and patented* Tera-Tomo™ 3D SPECT multi-GPU based reconstruction algorithm, including MRI-based attenuation and scatter corrections. Ultra-high resolution, artefact-free images are generated by 3D iterative algorithm based on on-the-fly Monte Carlo detector modeling with all physical corrections enabling quantification over the complete field of view. Resolution-booster™ is another novel design concept for the entire detection system that ensures the optimal alignment of the pinhole projections to the sensor (PMT) matrix that achieves 275 µm resolution confirmed by Derenzo phantom measurement.

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