Encouraging Outcomes Reported From Milan
Marta Scorsetti, M.D., director of the Department of Radiation Oncology and Radiosurgery at the Humanitas Cancer Center in Milan, Italy, presented her work evaluating the feasibility and efficacy of SABR in the treatment of both inoperable primary liver cancer and liver metastases. She reported on the results obtained with 67 patients treated for metastatic lesions, and 18 patients with primary HCC lesions.
While specific local tumor control and overall survival results varied, after a median follow-up of 12 months all groups showed acceptable rates of local tumor control and very little treatment related toxicity. No radiation induced liver disease (RILD) was detected, Dr. Scorsetti reported.

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Gated RapidArc for Treating Liver Cancer
Po-Ming Wang, M.D., chief radiation oncologist at Cheng Ching General Hospital in Taichung, Taiwan, summarized his experience using Varian's TrueBeam STx system to deliver gated RapidArc radiosurgery in the treatment of liver cancer. RapidArc speeds up highly precise radiosurgery treatments by constantly shaping and reshaping the treatment beam to match the shape of the tumor while delivering dose continuously as the treatment machine rotates around the patient. Gated RapidArc makes it possible to monitor patient breathing and compensate for tumor motion during a RapidArc treatment.
"With the TrueBeam STx, we are able to image the tumor during the treatment and adapt the treatment delivery in 'real time' based on observable changes," said Dr. Wang. "This helps us to better target the liver tumor and minimize the impact on surrounding critical organs like the duodenum or stomach. The gated RapidArc technique also helps to preserve more of the patient's normal liver volume."
"Varian was pleased to provide financial support for this important meeting, which was the first liver-specific SABR meeting to take place in the Asia Pacific region," said Clif Ling, Ph.D., director of advanced clinical research for Varian. "The meeting was attended by radiation oncology and hepatology professionals and designed to provide a platform for liver cancer experts in Taiwan to begin to form a consensus about how to use SABR-a relatively new capability in radiation oncology-to treat HCC. We hope that better understanding of the use of SABR for HCC will lead to improved treatment results."
1World Cancer Report 2008, Boyle P & Levin P eds., World Health Organization: International Agency for Research on Cancer; Lyon, France http://www.iarc.fr/en/publications/pdfs-online/wcr/2008/wcr_2008.pdf.