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First analysis of IORT with Xoft system as boost prior to whole breast irradiation

Press releases may be edited for formatting or style | December 07, 2016 Rad Oncology Radiation Therapy
NASHUA, NH, and SAN ANTONIO, TX, 6 December 2016 – iCAD, Inc. (Nasdaq: ICAD), an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the early identification and treatment of cancer, today announced that researchers will present updated data on the use of intraoperative radiation therapy (IORT) with the Xoft® Axxent® Electronic Brachytherapy (eBx®) System® during the San Antonio Breast Cancer Symposium (SABCS) in San Antonio, Texas. The data include results from a subset of patients who received IORT with the Xoft System as a boost prior to administration of whole breast radiation therapy (WBRT) in patients with early-stage breast cancer. The Xoft System and its suite of products will be showcased at SABCS in the Xoft booth (#257) from December 6-10, 2016.

“We are committed to providing advanced, value-based treatment options that have the potential to improve patients’ lives and allow them to return to their normal daily routines as soon as possible,” said Ken Ferry, CEO of iCAD. “This first-ever analysis of patients treated with IORT as a boost with the Xoft System presents encouraging results and offers clinical evidence to support the valuable benefits of this treatment option for early-stage breast cancer patients with certain risk factors.”

At the meeting, research from Alam M. Nisar Syed, MD, medical director, radiation oncology and endocurietherapy, Memorial Care Cancer Institute, Long Beach Memorial Medical Center, will be presented during Poster Session 1 on Wednesday, December 7, from 5:00 to 7:00 pm. Dr. Syed’s findings include updated data on the treatment of 898 patients with early-stage breast cancer using IORT with the Xoft System at 26 hospitals in the U.S. and Portugal. The findings show that 90 percent of patients had excellent-to-good cosmesis with low rates of high-grade adverse events and recurrences two years post-treatment with Xoft IORT. This data will be presented in poster #1632.
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Of these 898 patients, 44 presented additional risk factors and were subsequently treated with WBRT, thus receiving an IORT boost dose prior to conventional treatment. This subset of patients was reviewed independently from the primary study, and Dr. Syed will continue to follow them as a separate subset for the duration of the 10-year study. The findings thus far show that IORT using the Xoft System as a tumor-bed boost at the time of lumpectomy is safe, with low morbidity, excellent-to-good cosmetic results and mostly low-grade adverse events. This data will be presented in poster #1782.

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