Transforming the medical practice
Total research and education funding in 2016 was more than $1 billion ─ $523 million in Mayo Clinic funding and $482 million from external sources.

Medical innovation advancements include:
Near-total face transplant
In Minnesota, Mayo Clinic completed a near-total face transplant on a Wyoming man. The extensive, life-changing surgery performed by a multidisciplinary team of surgeons, physicians and other health professionals in summer 2016 will improve the patient’s ability to chew, swallow, speak, breathe and smell. The recipient, whose face was devastated by a gunshot wound at 21, is doing well.

Precision Medicine Initiative All of Us Research Program biobank
To serve as the national Precision Medicine Initiative All of Us Program biobank, Mayo received $142 million in National Institutes of Health funding over five years. The biobank, on the Minnesota and Florida campuses, will store and curate more than 35 million biospecimens from 1 million or more U.S. participants. The Precision Medicine Initiative aims to understand individual differences that contribute to health and disease.

Senescent cells research
Research found that senescent cells – cells that no longer divide and accumulate with age – negatively impact health and shorten life span by as much as 35 percent in normal mice. The results demonstrate that clearing senescent cells delays tumor formation, preserves tissue and organ function, and extends life span without observed adverse effects. If the science is translatable to humans, a drug may be able to eliminate senescent cells and have profound effects on health and life span, researchers say.

Alzheimer’s disease data
A treasure trove of data was made public from a study aimed at accelerating therapies for Alzheimer’s disease. The study details whole genome genotype and gene expression patterns on 2,655 individuals with and without dementia, and includes more than 842 million data points. Mayo Clinic invited other investigators to mine the molecular and clinical data sets.

Reinvesting in facilities, strategic initiatives
Mayo Clinic reported income from current activities of $475 million in 2016. These funds are committed to mission-advancing projects. Capital expenditures exceeded $600 million in 2016. These expenditures are part of a multiyear plan to continue to invest in an electronic health record and revenue cycle management integration project, and information technology infrastructure upgrades.

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