dismiss

Clean Sweep Live Auction on Thur. March 28th. Click to view the full inventory

DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
Current Location:
>
> This Story


Log in or Register to rate this News Story
Forward Printable StoryPrint Comment
Advertisement

 

 

Molecular Imaging Homepage

RadioMedix and Vect-Horus to develop brain theranostic agent for brain cancer Provide diagnosis and treatment of Glioblastoma Multiforme (GBM)

NIH awards $1.8 million to Magnetic Insight for neurovascular MPI Detects magnetic nanoparticle tracers, enables deep-tissue imaging

DOE to cut Moly-99 deals with four US firms Could be as much as $15 million per company, with partners matching awarded amounts

Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis

Dennis Durmis MITA names chair of board of directors

Researchers find new PET tracer that better detects melanoma than 18F-FDG 18F-P3BZA could become the new gold standard

RadioMedix scores $2 million contract for Targeted Alpha-emitter therapy Treatment for neuroendocrine tumors

FDA clears United Imaging's total-body PET scanner Creating 3D images of entire human body in 15-30 seconds

FDA clears MIM SurePlan molecular radiotherapy software Can measure the absorbed dose from MRT for individual patients

Rob Beanlands ASNC names president for 2019

PET/MR scans can assess pediatric cancer survivor health

by John W. Mitchell , Senior Correspondent
A Stanford research team has demonstrated that a single imaging test is effective in assessing whether pediatric cancer patients have sustained harm from their chemotherapy treatments.

"There is no dedicated imaging test that can detect chemotherapy-induced injuries of the brain, heart, and bones at an early stage and at once," lead author Dr. Ashok Joseph Theruvath, postdoctoral research fellow in the Molecular Imaging Program at the Stanford School of Medicine, told HCB News. "Our triple organ PET/MR imaging has great potential to fill this gap and help to detect early injuries before patients become symptomatic. This could then help us to prescribe interventions, which can prevent lifelong health problems. "

Story Continues Below Advertisement

THE (LEADER) IN MEDICAL IMAGING TECHNOLOGY SINCE 1982. SALES-SERVICE-REPAIR

Special-Pricing Available on Medical Displays, Patient Monitors, Recorders, Printers, Media, Ultrasound Machines, and Cameras.This includes Top Brands such as SONY, BARCO, NDS, NEC, LG, EDAN, EIZO, ELO, FSN, PANASONIC, MITSUBISHI, OLYMPUS, & WIDE.



The study was recently published in the journal Radiology.

With treatment advances, according to Theruvath, survival rates are improving for children with cancer. However, associated chemotherapy treatments can lead to complications.

While chemotherapy-related chronic organ injury has been studied previously, he said that his team wanted to find a way to spot such complications sooner. This will help patients avoid a variety of health issues, ranging from memory loss and neurological problems, to heart failure and bone and joint injuries. The findings rely on statistical linear regression, a basic element of medical artificial intelligence.

"A linear regression model is a predictive analysis, which is used to explain the relationship between one dependent variable and one or more independent variables," said Theruvath. "In our exam, we analyzed whether cumulative chemotherapy doses of cancer survivors would correlate with specific imaging findings on our PET/MR scan."

The study included combined brain, heart and bone examinations conducted within a 90-minute test on ten patients who were pediatric cancer survivors. Eight of the patients had abnormal findings, including six patients with clinical symptoms and two with no symptoms.

While the team concluded that the test could enable earlier intervention in pediatric cancer survivors to improve survivability, more research is needed. This is especially true given the high cost of PET/MR.

"Our results are preliminary, and they need to be confirmed in larger cohorts," Theruvath explained." We are planning to streamline our protocol further so it can be integrated into the clinical setting."

He added that as a next step, the team is developing a screening test based on a blood sample. This test should identify patients who are hypersensitive to certain chemotherapeutic agents and at risk for specific tissue injuries. These patients who test positive for sensitivity, he said, could then be referred to the PET/MR imaging test.

He also noted that they expected that patients who received higher cumulative chemotherapy doses would show more severe tissue damage after chemotherapy.

The team found an overall trend toward such a relationship, but also noted that there were outliers. This includes patients who either received very high doses and had little or no tissue injuries, and patients who received relatively low doses and showed quite extensive tissue injuries.

"Since there is no clear relationship between chemotherapy dose and toxic effect, imaging plays an important role in determining who has encountered damage to which tissue as a result of their therapy," he said.

Theruvath added that in principle, the triple organ scan for cancer survivors could not only be offered to survivors of pediatric cancers, but also to adult patients.

Molecular Imaging Homepage


You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2019 DOTmed.com, Inc.
ALL RIGHTS RESERVED