LAS VEGAS, February 23, 2018 /PRNewswire/ -- Despite significant technological advances in technology, cardiovascular diseases (CVDs) remain the number one cause of death globally. CVDs are a group of disorders of both the heart and blood vessels that can lead to heart attacks and strokes. The history of treatment for CVDs is extensive, but as we move forward in medical research, three distinctive treatments are truly changing lives. Included in today's commentary: Endonovo Therapeutics, Inc. (OTC: ENDV), 22nd Century Group, Inc. (NYSE: XXII), Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP), Emerald Health Therapeutics, Inc. (TSX-V: EMH) (OTC: EMHTF), Delcath Systems, Inc. (OTC: DCTH)

The first is a new treatment for high cholesterol, a drug therapy called PSCK9 inhibitor. This inhibitor has been shown to reduce bad cholesterol (LDL-C) by as much as 50 to 70 percent with little negative effects. This has proved to be helpful for patients who cannot take statins because of horrible adverse effects.

Congestive heart failure is a common disorder characterized by a failure of the heart muscle to forcefully pump blood to the body's tissues. Patients often suffer from severe shortness of breath and a low quality of life. The second treatment giving hope for patients is a drug by the name of LCZ696 and proves to be highly effective in clinical trials. It achieved a substantial 20 percent reduction in death or repeat hospitalization compared with the best currently available therapies.

The third and most innovative therapy are non-invasive medical devices called Electroceuticals that deliver electrical pulses to inflamed tissues like the heart following a heart attack. Most CVDs are caused by atherosclerosis, a disease process that causes thickening of the arterial wall because of inflammation and lipid accumulation, resulting in plaque formation. Electroceuticals target the underlying issue of CVDs: inflammation and restricted blood flow. This technology can be used across medical issues as it targets inflammation, an underlying component of many diseases like chronic kidney failure, non-alcoholic steatohepatitis (NASH), stroke and diabetes.

It is through the development of new drugs and therapies that the biotech world hopes to change the outcome for patients suffering from CVDs, and lower its rank on the list as number one cause of death globally.

In other biotech news, check out Endonovo Therapeutics, Inc. (OTCQB: ENDV), 22nd Century Group, Inc. (XXII), Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP), Emerald Health Therapeutics, Inc. (CVE: EMH) (OTCQX: EMHTF), and Lexington Biosciences, Inc.

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