7. Improvised Use of Medical Devices—Modified devices, workflow, or systems may lead to serious safety and regulatory compliance issues.
8. Methotrexate Therapy—The weekly administration of this cancer drug—also in use for autoimmune diseases—leads to dosing and dosing frequency errors.
9. Peripheral Vascular Harm—Severe cases of injury and infection can lead to extended lengths of stay and antibiotic treatments—even death.
10. Infection Risk from Aerosol-Generating Procedures—The exposure risk from performing aerosol-generating procedures on suspected COVID-19 patients is very high.

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ECRI’s Top 10 Patient Safety Concerns for 2021 provides detailed steps that organizations can take proactively to prevent adverse incidents and is available for public download. ECRI is also hosting a complimentary Top 10 Patient Safety Concerns webinar on Thursday, March 18, to explain how the list can be used to enhance safety in healthcare organizations across all care settings.
About ECRI
ECRI is an independent, nonprofit organization improving the safety, quality, and cost-effectiveness of care across all healthcare settings. With a focus on patient safety, evidence-based medicine, and health technology decision solutions, ECRI is respected and trusted by healthcare leaders and agencies worldwide. Over the past fifty years, ECRI has built its reputation on integrity and disciplined rigor, with an unwavering commitment to independence and strict conflict-of-interest rules.
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