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The latest in cancer treatment technology

by Lisa Chamoff, Contributing Reporter | October 18, 2021
Rad Oncology
From the October 2021 issue of HealthCare Business News magazine


The device has an extended gantry range and quick-connect collimator system to better access the patient and can cut treatment from 20 minutes to seven to eight minutes.

“We saw an opportunity to optimize the system and make electron treatments convenient and more accessible for these patients,” said Derek DeScioli, chief executive officer of IntraOp Medical.

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The first two systems have been installed in the U.S. The company also expanded its Prelude software to manage skin cancer patients.

In July, the company announced a preclinical phase I trial of FLASH radiotherapy in patients with skin metastases from melanoma at Lausanne University Hospital in Switzerland. The Mobetron platform was enhanced to deliver ultra-high dose rates with electrons.

The company expects that two other clinical partners will be opening investigative trials next year.

Leo Cancer Care
Leo Cancer Care offers a radiotherapy treatment system with positioning that allows treatment to be delivered in a seated position with rotation of the patient, instead of the heavy equipment, along with dual-energy CT.

Stephen Towe, the chief executive officer of Leo Cancer Care, co-founded by medical physicist Thomas “Rock” Mackie, says the seated position allows for less organ movement and ensures the lungs are more inflated.

“We've really turned this on its head and reduced the size, cost and complexity of radiation therapy,” Towe said.

Earlier this year, the company installed its first particle therapy-compatible system, called Marie, in Europe. The system includes the patient positioning device and a dual-energy multi-access fan beam CT scanner.

“Particle therapy is delivered mostly in larger centers,” Towe said. “The Leo Cancer Care system brings the cost down so dramatically you can really use the phrase ‘democratizing particle therapy’.”

Photon therapy systems are currently in development.

RefleXion Medical
The RefleXion X1, which combines fan-beam CT with a linear accelerator, was FDA cleared March 2020 to provide stereotactic body radiation therapy (SBRT), stereotactic radiosurgery (SRS) and intensity-modulated radiation therapy (IMRT).

The company is pursuing FDA approval for biology-guided radiotherapy (BgRT) using PET and CT imaging with the system, which offers the “promise of tumors being biological beacons,” said Sam Mazin, RefleXion Medical’s founder and chief technology officer.

BgRT using the X1 is being studied clinically by the Stanford Cancer Institute and University of Texas Southwestern in Dallas under an investigational device exemption, looking at BgRT feasibility and workflow to gain FDA approval, possibly under the De Novo pathway.

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