DOSIsoft, leading provider of patient-specific imaging and dosimetry software solutions for Radiation Oncology and Nuclear Medicine, is proud to announce its latest innovation - ThinkQA Secondary Dose Check – a fast, reliable, and independent 3D dose calculation for online adaptive workflows.
CE marked on April 14th, 2023, the new software product will succeed the current MU2net solution and offers a technology breakthrough and cost-effective solution for Secondary dose calculation and verification. It will be of great value for Radiation Therapy (RT) departments to perform routine Patient-specific Quality Assurance (QA) and meet the QA requirements of the latest adaptive radiotherapy equipment and practices.
Fast and reliable 3D secondary dose calculation and verification for adaptive RT market

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Resulting from 3 years of intense Research & Development, leveraging DOSIsoft dose calculation and Treatment Planning System (TPS) expertise, ThinkQA Secondary Dose Check combines dose computation accuracy, relevant dose comparison metrics, and ergonomic web design to provide a fast and reliable secondary dose check.
The advanced model-based independent 3D dose calculation engine, a specifically adapted Collapsed Cone Convolution (CCC) algorithm – is compatible with both conventional and adaptive RT workflows.
Intuitive and user-friendly, the ThinkQA web platform and dashboard allow comparison of 3D dose distributions, with key dosimetric indicators, such as whole matrix differential and cumulative DVH (Dose Volume Histograms) and Gamma Index Agreements (GAI) on automatic or target volumes.
Compliant with AAPM Task Group 219(1) recommendations
The implementation of new treatment techniques in External Beam Radiation Therapy (EBRT) departments increases the complexities in dose planning and delivery, thus the potential for serious errors or uncertainties. It is also even more true for the new adaptive radiotherapy. Catching errors before actual RT treatment begins is an essential part of verification steps for a complete Patient QA.
The recent AAPM Task Group 219 has issued specific recommendations, to help physicists address these challenges and meet QA regulatory compliances. ThinkQA Secondary Dose Check complies with these AAPM recommendations, in particular:
- Fast, simple and automated system to be used for every plan
- 3D dose distribution comparison providing analysis with respect to specific automatic volumes (High dose, High gradient, Mean dose and Low dose) as well as 3D Gamma Passing Rates (GPR) for High Dose / High Gradient regions and PTVs