by
Barbara Kram, Editor | November 28, 2005
* University of Nebraska Medical Center, Omaha, Neb.
Principal Investigator: Wing C. Chan, M.D.
This project will refine and validate diagnostic and prognostic molecular signatures for the major subclasses of non-Hodgkin's lymphoma using the LymphDX chip that was developed for the project by the Affymetrix company.
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* University of New Mexico, Albuquerque, N.M.
Principal Investigator: Cheryl L. Willman, M.D., Ph.D.
This project will refine and confirm molecular signatures that improve risk classification, outcome prediction, therapeutic response, and risk of relapse in pediatric and adult acute lymphocytic leukemia.
* Vanderbilt-Ingram Cancer Center, Nashville, Tenn.
Principal Investigator: David P. Carbone, M.D., Ph.D.
This project will refine and evaluate molecular signatures in lung cancer, including serum proteomic signatures that differentiate patients with cancer from those without disease, and provide signatures that predict risk of recurrence following surgery.
* Washington University, Department of Medicine, St. Louis, Mo.
Principal Investigator: Matthew J. Ellis, M.D., Ph.D.
This project will refine and validate molecular signatures that identify five subtypes of breast tumors using the technology, quantitative polymerase chain reaction, to measure signatures in fixed tissues.
For additional information about SPECS and NCI's Cancer Diagnosis Program, please visit: http://www.cancerdiagnosis.nci.nih.gov/.
For more information about cancer, visit the NCI Web site at http://www.cancer.gov, or call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237).
The National Institutes of Health (NIH) -- The Nation's Medical Research Agency -- includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary Federal agency for conducting and supporting basic, clinical, and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.
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