by
Lynn Shapiro, Writer | September 30, 2009
The Wong group uses optical tweezers to study the behavior of single molecules under force in order to reveal the nanoscopic workings of biological systems. Together with their collaborators, they have used this approach to expose the molecular feedback mechanism behind the regulation of blood clotting and to determine the dynamic mechanical properties of spectrin, a structural molecule largely responsible for the amazing material properties of red blood cells. (Paper FWS1, High-Resolution, High-Stability, "High-Frequency Optical Tweezers Method with a Simple Video Camera" is at 1:30 p.m. Wednesday, Oct. 14).
Source: Optical Society
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