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FDA: Newer Breast Cancer Drug Better

January 02, 2006

From CNN Health - December 29, 2005 08:04


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(AP) -- Women now have another drug they can take to prevent breast cancer from returning after surgery to remove the tumor.

The federal Food and Drug Administration on Wednesday approved a new use for Femara, a medication already licensed for treating advanced breast cancer. It now can be given as initial therapy to women past menopause who have early breast cancer, the agency said.

In Thursday's New England Journal of Medicine, a study reports that Femara was more effective at preventing recurrences than the current gold standard, tamoxifen.

Femara and Arimidex, a similar drug already licensed for early breast cancer, are aromatase inhibitors, which block production of estrogen, a hormone that fuels the growth of most tumors that develop after menopause. Tamoxifen works differently, by blunting the ability of estrogen to enter cells.