Uncovering How Bone Marrow Stromal Cells Can Potentially Regenerate Brain Tissue

by Barbara Kram, Editor | March 25, 2006

Molecular imaging and nuclear medicine are useful tools that allow the visualization of different kinds of neuronal functions to evaluate cell transplantation therapy in both experimental and clinical situations, said Kuroda. "It is very difficult to visualize neuronal functions; therefore, we chose receptor imaging to assess the effects of cell transplantation therapy on cerebral stroke," he explained.

Besides Kuroda, co-authors of "Improved Expression of ?-Aminobutyric Acid Receptor in Mice With Cerebral Infarct and Transplanted Bone Marrow Stromal Cells: An Autoradiographic and Histologic Analysis" include Hideo Shichinohe, M.D., Ph.D., Shunsuke Yano, M.D., Ph.D., Kazutoshi Hida, M.D., Ph.D., and Yoshinobu Iwasaki, M.D., Ph.D., all with the department of neurosurgery at Hokkaido University Graduate School of Medicine in Sapporo, Japan; and Takako Ohnishi, MSc, and Hiroshi Tamagami, MSc, both in the research and development division, Research Center, Nihon Medi-Physics Co. Ltd., Sodegaura, Japan.

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Media representatives: To obtain a copy of this article and related images, please contact Maryann Verrillo by phone at (703) 708-9000, ext. 1211, or send an e-mail to mverrillo@snm.org. Current and past issues of the Journal of Nuclear Medicine can be found online at jnm.snmjournals.org. Print copies can be obtained by contacting the SNM Service Center, Society of Nuclear Medicine, 1850 Samuel Morse Drive, Reston, VA 20190-5316; phone (800) 513-6853; e-mail servicecenter@snm.org; fax (703) 708-9015. A subscription to the journal is an SNM member benefit.

About SNM
SNM is an international scientific and professional organization of more than 16,000 members dedicated to promoting the science, technology and practical applications of molecular and nuclear imaging to diagnose, manage and treat diseases in women, men and children. Founded more than 50 years ago, SNM continues to train physicians, technologists, scientists, physicists, chemists and radiopharmacists in state-of-the-art imaging procedures and advances; provide essential resources for health care practitioners and patients; publish the most prominent peer-reviewed resource in the field; sponsor research grants, fellowships and awards; and host the premier annual meeting for medical imaging. SNM members have introduced--and continue to explore--biological and technological innovations in medicine that noninvasively investigate the molecular basis of diseases, benefiting countless generations of patients. SNM is based in Reston, Va.; additional information can be found online at www.snm.org.

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