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Medtronic Announces First Implants in Largest-Ever, Global Trial of Cardiac Resynchronization Therapy

Press releases may be edited for formatting or style | August 27, 2014
Patients with AdaptivCRT demonstrated a 21 percent reduction in heart failure hospitalizations2 as compared to historical CRT trials
Patients with the AdaptivCRT technology demonstrated a 46 percent reduced risk of AF3, and a 61 percent lower risk of AF-related problems4
AdaptivCRT demonstrated a reduction in 30-day hospital readmissions for heart failure of 47 percent5
In the U.S., approximately 5.1 million people suffer from heart failure6 and the estimated cost for treating heart failure is approximately $40 billion per year.7 Worldwide, more than 23 million people suffer from heart failure.8,9 The disease consumes intensive resources during hospitalizations and continues to cause problems following hospital stays, with six month readmission rates of 50 percent10, 11, 12 and mortality rates of approximately 30 percent.13 Repeated heart failure hospitalizations also are associated with increased mortality.

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"Medtronic is committed to improving the lives of people with heart failure at every stage of their care, including those who can benefit from cardiac resynchronization therapy," said David Steinhaus, M.D., vice president and general manager, Heart Failure, and medical director for the Cardiac Rhythm Disease Management business at Medtronic. "With the AdaptivCRT algorithm improving patient response to CRT, we see fewer heart failure complications, and fewer burdens imposed on patients and healthcare resources."

In collaboration with leading clinicians, researchers and scientists worldwide, Medtronic offers the broadest range of innovative medical technology for the interventional and surgical treatment of cardiovascular disease and cardiac arrhythmias. The company strives to offer products and services that deliver clinical and economic value to healthcare consumers and providers around the world.

About Medtronic
Medtronic, Inc. (www.medtronic.com), headquartered in Minneapolis, is the global leader in medical technology - alleviating pain, restoring health, and extending life for millions of people around the world.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.

Contacts:

Tracy McNulty
Public Relations
+1-763-526-2492

Jeff Warren
Investor Relations
+1-763-505-2696

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