The CoreValve System was approved by the FDA in 2014 for patients at extreme risk and high risk for surgery, and received CE (Conformité Européenne) Mark for VIV procedures in May 2013. The CoreValve System has been implanted in more than 75,000 patients in more than 65 countries since receiving CE Mark in 2007. In addition, the CoreValve System offers the broadest range of sizes available to accommodate more patients.
In collaboration with leading clinicians, researchers and scientists worldwide, Medtronic offers the broadest range of innovative medical technology for the interventional and surgical treatment of cardiovascular disease and cardiac arrhythmias. The company strives to offer products and services that deliver clinical and economic value to healthcare consumers and providers around the world.

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About Medtronic
Medtronic plc (www.medtronic.com), headquartered in Dublin, Ireland, is the global leader in medical technology - alleviating pain, restoring health and extending life for millions of people around the world.
Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.
i Brown JM et al; The Journal of Thoracic and Cardiovascular Surgery; V.137; No.1; 1/09; p82
ii Dvir, D. et al. "Transcatheter Aortic Valve Replacement for Degenerative Bioprosthetic Surgical Valves: Results From the Global Valve-in-Valve Registry." Circulation. October 2012.
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