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Mayo researchers examine risk factors/patient outcomes associated with colorectal cancer

Press releases may be edited for formatting or style | September 01, 2015

"Our primary aim was to establish the magnitude of risk that each component operation, both liver and colon, contributed to synchronous resections in order to determine which combination of colon and liver operations were most safe to be performed at the same time," says Dr. Nagorney.

While past studies had only considered the extent of liver resected performed, Mayo researchers also reviewed the type or location of colorectal resection.

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"We wanted to test the hypothesis that both the extent of the liver resection and the location or type of colorectal resection influence the overall risk and patient outcomes associated with these operations," says the article's first author, Christopher Shubert, M.D., who is also a surgeon and Kern Scholar at Mayo Clinic.

The researchers assigned risk categories to each of the operations performed in the data pool, including colorectal and liver resections, and then compared 30-day postsurgical outcomes among patients within similar risk groups. They also compared outcome data between two groups of patients within each risk category - those who had synchronous colorectal and liver resections and those who had these operations sequentially.

"Stratifying patients using risk categories allowed us to make more accurate comparisons between patient outcomes associated with synchronous versus sequential resections," says Dr. Shubert.

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This study was made possible in part by the Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery and the Surgical Outcomes Program within the center, which is led by study co-authors Elizabeth Habermann, Ph.D., and Robert Cima, M.D. Other co-authors, also from Mayo Clinic, included John Bergquist, M.D.; Cornelius Thiels, D.O.; Kristine Thomsen; Walter Kremers, Ph.D.; and Michael Kendrick, M.D.

About Mayo Clinic

Mayo Clinic is a nonprofit organization committed to medical research and education, and providing expert, whole-person care to everyone who needs healing. For more information, visit mayoclinic.com or newsnetwork.mayoclinic.org.

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