"The results of the PREDIMED trial suggest a beneficial effect of a MeDiet [Mediterranean diet] supplemented with EVOO in the primary prevention of breast cancer. Preventive strategies represent the most sensible approach against cancer. The intervention paradigm implemented in the PREDIMED trial provides a useful scenario for breast cancer prevention because it is conducted in primary health care centers and also offers beneficial effects on a wide variety of health outcomes. Nevertheless, these results need confirmation by long-term studies with a higher number of incident cases," the authors conclude.
Editor's Note: Can Diet Prevent Breast Cancer?
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In a related editor's note, Mitchell H. Katz, M.D., a deputy editor of JAMA Internal Medicine, writes: "Of course, no study is perfect. This one has a small number of outcomes (only 35 incident cases of breast cancer), the women were not all screened for breast cancer with mammography, they were not blinded to the type of diet they were receiving, and all were white, postmenopausal and at high risk for cardiovascular disease. Still, consumption of a Mediterranean diet, which is based on plant foods, fish and extra virgin olive oil, is known to reduce the risk of cardiovascular disease and is safe. It may also prevent breast cancer. We hope to see more emphasis on Mediterranean diet to reduce cancer and cardiovascular disease and improve health and well-being."
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(JAMA Intern Med. Published online September 14, 2015. doi:10.1001/jamainternmed.2015.4838. Available pre-embargo to the media at http://media.jamanetwork.com.)
Editor's Note: Authors made conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures
Media Advisory: To contact study corresponding author Miguel A. Martínez-González, M.D., email Jesus Diaz at jediaz@unav.es or call +34-636-355-333. To contact Editor's Note author Mitchell H. Katz, M.D., email mediarelations@jamanetwork.org
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