Substantial weight loss not only slows knee joint degeneration—it also reduces the risk of developing osteoarthritis, Dr. Gersing said. Along with moderate exercise, weight loss is one of the primary interventions against the disease.
"It's most helpful if these lifestyle interventions take place as early as possible," Dr. Gersing said.

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In the future, the researchers are planning to study the role of diabetes, which is closely linked with obesity, in cartilage degeneration. They also plan to do an eight-year follow-up with the patient group and look at what effects weight gain may have on the knee joint.
Co-authors on the study are Martin Solka, Gabby B. Joseph, Ph.D., Benedikt J. Schwaiger, M.D., Ursula R. Heilmeier, M.D., Georg Feuerriegel, John Mbapte Wamba, M.D., Charles E. McCulloch, Ph.D., Michael C. Nevitt, Ph.D., and Thomas M. Link, M.D., Ph.D.
Note: Copies of RSNA 2015 news releases and electronic images will be available online at RSNA.org/press15 beginning Monday, Nov. 30.
RSNA is an association of more than 54,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on musculoskeletal MRI, visit RadiologyInfo.org.
SOURCE Radiological Society of North America (RSNA)
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