SUNNYVALE, Calif., May 11, 2017 /PRNewswire/ -- Accuray Incorporated (NASDAQ: ARAY) announced today that studies on the clinical use of the leading-edge CyberKnife® System continue to demonstrate its benefits across a wide range of cancer indications and stages in the cancer treatment journey. More than 50 studies were presented during poster and oral sessions at the 36th Annual European Society for Radiotherapy & Oncology (ESTRO) Meeting in Vienna, Austria, May 5 - 9, 2017. Some of the studies presented show long-term efficacy and safety with median follow-up exceeding five years.
CyberKnife stereotactic body radiation therapy (SBRT) is used worldwide for effective management of prostate cancer
Safety, efficacy, and quality of life (QOL) outcomes were reported for 309 patients with low- or intermediate-risk prostate cancer receiving SBRT administered with the CyberKnife System. The study showed cancer control was excellent in both risk groups with 97% of patients free from recurrence at five years. Transient decreases in bowel and urinary QOL were observed, but returned to baseline. Twenty-one U.S. hospitals participated in this prospective study including Swedish Cancer Institute in Seattle, Washington and Beth Israel Deaconess Medical Center in Boston, Massachusetts.
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A study evaluated the long-term results of CyberKnife prostate SBRT delivered either on consecutive days or every other day. The treatment was well-tolerated with high rates of five-year biochemical relapse free survival (BRFS). Low rates of toxicity were unaffected by the treatment schedule. The research was conducted at the Hacettepe University in Ankara, Turkey.
Long-term results of another study conducted on 329 patients with low- and intermediate-risk prostate cancer revealed that extreme hypofractionated radiotherapy delivered with the CyberKnife System is well tolerated and safe with comparable late toxicity as other treatment modalities. Clinicians of the Erasmus MC Cancer Institute, in Rotterdam (The Netherlands) conducted the study.
The CyberKnife System provides benefits for primary cases, recurrent and metastatic diseases
Recurrent Disease
Although re-irradiation of recurrent diseases can be challenging in clinical practice, four European studies confirmed its feasibility in prostate and rectal cancer, as well as in recurrent high grade gliomas. These studies concluded that re-irradiation with the CyberKnife System is well-tolerated and effective in controlling local recurring disease.
