"What's important about these findings is that for older patients, the stakes are often considerably higher because of potential comorbidities (e.g., bone loss), shorter life expectancies, quality of life (QoL) concerns, and overall life expectancy etc.," said Dr. Schnabel. "BCI identified patients likely to benefit from EET, but perhaps most importantly for this age group, those for whom EET would be unlikely to show benefit. This additional information can be very helpful to clinicians in treatment planning for older patients."
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Additional Studies
Other new data supporting the clinical utility can be found published in the Journal of Clinical Oncology in conjunction with the annual meeting. Those abstracts include:
Likelihood of late relapse assessed by the Breast Cancer Index (BCI) in LN-invasive lobular compared to invasive ductal carcinoma (abstract #: e12025)
Correlation of Breast Cancer Index (BCI) prognostic and predictive results to Ki67 and tumor grade in early stage HR+ breast cancer. (abstract #: e12075)
About Breast Cancer IndexSM
BCI is a molecular, gene expression‑based test uniquely positioned to help identify patients best suited for extended endocrine treatment. It is the only validated, commercially available test with data demonstrating prognostic risk of recurrence out to 15 years, as well as prediction of likelihood of benefit from extended endocrine therapy (treatment in years 5‑10). The breakthrough test helps oncologists and patients navigate the difficult trade‑off between wanting to take steps to prevent recurrence of their disease and facing significant side effects and safety challenges related to extended endocrine therapy. For more information, visit www.breastcancerindex.com.
About Biotheranostics
Biotheranostics, Inc., is a leader in helping physicians improve the care of cancer patients, offering a suite of proprietary molecular diagnostic tests that allow treatment to be tailored to individual patients. The company's CancerTYPE ID® is the most rigorously validated gene expression test for metastatic patients with diagnostic ambiguity, helping physicians determine optimal site‑directed treatment regimens with the goal of improving patient outcomes. Its Breast Cancer IndexSM helps oncologists make difficult decisions about extended endocrine therapy for ER+ breast cancer patients based on its unique ability to predict risk of late disease recurrence and identify which patients are likely to benefit from continuing therapy beyond five years. Biotheranostics is based in San Diego. For more information, visit www.biotheranostics.com.
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