DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
Current Location:
>
> This Story


Log in or Register to rate this News Story
Forward Printable StoryPrint Comment

 

MRI Homepage

What’s new in MR scanners and coils? A review of new innovations arriving on market

Purchasing Insights: The ABCs of buying an MR Facilities must think about their scanning needs of tomorrow when investing today

Siemens gets 7T MR cleared for clinical use in US MAGNETOM Terra offers benefits for neuro and MSK imaging

Contrasting viewpoints on gadolinium Despite evidence of harm, the industry worries about brain retention

Anthem presses forward with new MR, CT reimbursement guidelines An effort to increase usage of free-standing scan facilities

Merry X-Ray acquires Consensys Imaging Service Expands presence in MR, CT and other imaging modality markets

The future of AI in MR: Supporting clinical decisions Insights from Murat Gungor, vice president of Magnetic Resonance (MR) at Siemens Healthineers North America

MR shielding: out of sight, but hopefully not out of mind Insights from the experts on installation and RF shield maintenance

MR better at detecting Zika fetal brain abnormalities than ultrasound alone Provides greater detail regarding brain structures

The unique challenges of keeping the MR environment clean Eliminating bacteria in the magnetically charged MR suite

A new study indicates that newborns
with CHD may start developing
neurological impairments before cardiac
surgery is even performed

MR detects neurological impairments in newborns with CHD before surgery

by John Fischer , Staff Reporter
Newborns with congenital heart disease (CHD) may develop signs of neurological impairments earlier than originally thought.

Researchers at Children’s National Health System have found for the first time reduced functional connectivity between specific areas of the brain in babies born with CHD before cardiac surgery was even performed. Their findings were revealed through the use of resting state functional connectivity magnetic resonance imaging (rs-fcMR).

Story Continues Below Advertisement

The (#1 Resource) for Medical Imaging and Peripherals. Call 1-949-273-8000

As a Master Distributor for major brands Barco, Philips, and Sony, we offer custom imaging solutions. With our renowned OEM Solutions and Service/Repair Center, Ampronix is a one-stop shop for HD Medical LCD Displays--Printers--Recorders--4K Cameras



“When you scan your brain in a conventional scan, it’s a static picture,” Josepheen De Asis-Cruz, a research post-doctoral fellow in the Developing Brain Research Laboratory at Children's National and the lead author of the study, told HCB News. “For these babies, what we’re doing is resting state functional connectivity MR. The difference is that instead of one picture, we’re getting a video. We’re getting a series of images. Instead of taking a snapshot of the brain, it’s a continuous set of images that allows you to determine how different regions of the brain are associated with each other."

Conventional MR produces a static picture for assessing the structure of the brain while rs-fcMR creates a video depicting a series of continuous images that provide insight into the development of brain function, with information obtained from characterizing irregular rising and falling blood oxygen level-dependent signals from different regions of the brain.

For their study, researchers compared whole brain functional connectivity in 82 healthy, full-term newborns and 30 who suffered from CHD before undergoing corrective heart surgery. Conventional imaging showed no signs of brain injury in both groups but rs-fcMR results reported lower weights and reduced APGAR scores one and five minutes following birth for babies with CHD.

Subjects with the condition were found to have intact global network topologies. Closer studies of specific brain regions found functional disturbances in a subnetwork of nodes, particularly ones involving the subcortical regions. Weaker functional connectivity between right and left thalamus and between right thalamus and the left supplementary motor area were also noticed.

Areas of the brain with reduced functional connectivity matched regional brain abnormalities revealed in imaging studies which relied on conventional MR and diffusion tenor imaging.

More than 50 percent of newborns with CHD experience neurological damage in the form of motor problems, cognitive problems and social behavioral difficulties that manifest years after their birth.

Catherine Limperopoulos, the director of the Developing Brain Research Laboratory at Children’s National and the senior author of the study, says the use of rs-fcMR will provide physicians with the ability to identify signs of neurological impairments years before they develop.

“It’s hard to say exactly what effects impaired functional connectivity will have,” she told HCB News. “We postulate, however, that our ability to now be able to pick up disturbances in the emerging functional connectivity of the brain in newborns with congenital heart disease will allow us to be able to identify early biomarkers for long-term neurodevelopmental disabilities that will take years to manifest.”

The study was published in NeuroImage: Clinical.

MRI Homepage


You Must Be Logged In To Post A Comment

Advertise
Increase Your
Brand Awareness
Auctions + Private Sales
Get The
Best Price
Buy Equipment/Parts
Find The
Lowest Price
Daily News
Read The
Latest News
Directory
Browse All
DOTmed Users
Ethics on DOTmed
View Our
Ethics Program
Gold Parts Vendor Program
Receive PH
Requests
Gold Service Dealer Program
Receive RFP/PS
Requests
Healthcare Providers
See all
HCP Tools
Jobs/Training
Find/Fill
A Job
Parts Hunter +EasyPay
Get Parts
Quotes
Recently Certified
View Recently
Certified Users
Recently Rated
View Recently
Certified Users
Rental Central
Rent Equipment
For Less
Sell Equipment/Parts
Get The
Most Money
Service Technicians Forum
Find Help
And Advice
Simple RFP
Get Equipment
Quotes
Virtual Trade Show
Find Service
For Equipment
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2017 DOTmed.com, Inc.
ALL RIGHTS RESERVED