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University of Rochester Advances New Imaging Technology

by Barbara Kram, Editor | April 02, 2007

"Radiologists have attempted to compensate for these problems by doing faster scans and then once they have image they filter it to decrease the artifact," said Chengazi. "But these artifacts are already 'baked' into the image by the process of reconstruction."

The T.I.E.S. technology overcomes these problems by segmenting the raw data before it is converted into an image. This allows radiologists to exclude objects that are not of interest and, thereby, heighten the resolution of the remaining target image. To draw a comparison, this approach is roughly analogous to why it is more effective to make scientific observations of the sun's corona - or atmosphere - during a solar eclipse when the body of the sun is obstructed.

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Chengazi began to develop this method when he was a Ph.D. student at the University of London. After arriving in Rochester, Chengazi approached Umar Riaz, a computer engineer with T.I.E.S., who converted the mathematical algorithms into the software code that is the foundation of the current version of the technology.

The Image Surgery technology, which could represent a fundamentally new direction in medical tomography, has a potentially vast application in clinical care and biomedical research in fields such as cancer, musculoskeletal conditions and cardiovascular disease. Under the research agreement, the raw data from the University's nuclear medicine gamma cameras will be run through the T.I.E.S. software so that scientists can compare it with the image generated using standard technologies. The technology is applicable to other types of scanners as well. The company plans to haveits first image enhancement product for SPET (Single-Photon Emission Tomography) applications commercially available by next year.

T.I.E.S. was founded in 2003 by Chengazi, Sandhu, K. Bradley Paxton, Ph.D., and URMC internist Bilal Ahmed, M.D. Sandhu and Paxton are both former Kodak executives and are also founders of ADI, LLC, a Rochester-based data quality management company which provides products and services to clients such as United States Census Bureau.

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